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Reason for acomplia using: Acomplia (Rimonabant) - Investigational Agent for the Management of Obesity
Developed by Sanofi-Aventis, Acomplia (rimonabant) is a selective CB1 endocannabinoid receptor antagonist indicated for the treatment of obesity. It works by blocking endogenous cannabinoid binding to neuronal CB1 receptors. Activation of these receptors by endogenous cannabinoids, such as anadamide, increases appetite.
In the prevailing market there is a clear opportunity for an effective and well-tolerated anti-obesity drug. Although Acomplia (rimonabant) appeared efficacious, like previous anti-obesity drugs, safety issues have led to its withdrawal.
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